Best Four-Cheese Macaroni and Cheese (2024)

Bring a large pot of lightly salted water to boiling. Add pasta and cook according to package directions. Drain and return to the warm pot.

Meanwhile, in a large saucepan melt the 3 tablespoons butter over medium heat. Add onion; cook and stir for 3 minutes. Stir in flour, kosher salt, and pepper.

Add milk all at once. Cook, whisking constantly, until thickened and bubbly. Cook and whisk for 2 minutes more. Remove from heat.

Add Gouda cheese, cheddar cheese, Swiss cheese, and 1/4 cup of the Parmesan cheese, whisking until cheeses are melted and sauce is smooth.

In a small microwave-safe bowl melt the 1 teaspoon butter. Stir in panko and the remaining 1/4 cup Parmesan cheese. Sprinkle panko mixture over pasta mixture. Broil in a baking dish that is 5 to 6 inches from the heat for about 2 minutes or until the top is browned. If desired, garnish with parsley.

Bacon-Blue Macaroni and Cheese Variation

Prepare Four-Cheese Macaroni and Cheese as directed, except stir 3 slices crisp-cooked, drained, and crumbled bacon and 1/4 cup crumbled blue cheese (1 ounce) into panko mixture before sprinkling over pasta mixture.

Nutrition analysis per serving: 781 calories, 39 g protein, 72 g carbohydrate, 37 g total fat (22 g sat. fat), 120 mg cholesterol, 3 g fiber, 9 g total sugar, 21% Vitamin A, 2% Vitamin C, 1029 mg sodium, 80% calcium, 18% iron

Butternut Squash Macaroni and Cheese Variation

Prepare Four-Cheese Macaroni and Cheese as directed, except preheat oven to 450°F. Coat a 15x10x1-inch baking pan with nonstick cooking spray. Place 1 1/2 pounds butternut squash, peeled, seeded, and cut into 1-inch cubes, in the prepared baking pan. Drizzle 2 tablespoons olive oil over squash pieces; toss to coat. Roast, uncovered, for 25 to 30 minutes or until tender, stirring occasionally. Stir cooked squash into pasta with the cheese sauce.

Nutrition analysis per serving: 822 calories, 37 g protein, 83 g carbohydrate, 38 g total fat (21 g sat. fat), 111 mg cholesterol, 5 g fiber, 11 g total sugar, 213% Vitamin A, 30% Vitamin C, 862 mg sodium, 81% calcium, 21% iron

Cajun Shrimp and Sausage Macaroni and Cheese Variation

Prepare as directed, except use dried rigatoni or ziti for the pasta, omit salt in the white sauce, and omit Parmesan cheese in the cheese sauce and in the crumb topper. In a 6-inch skillet heat 2 teaspoons vegetable oil over medium. Add 1/2 cup each chopped red bell pepper, green bell pepper, and celery; cook and stir 5 minutes or until softened. Remove from skillet. Add 8 ounces sliced, cooked andouille sausage to skillet; cook and stir over medium heat until browned. Whisk 8 ounces shredded Gouda cheese, 4 ounces shredded Swiss cheese, 2 ounces each shredded sharp cheddar and torn American cheeses, and 2 teaspoons Cajun seasoning into White Sauce. Stir pepper mixture, sausage, and 8 ounces peeled and deveined, small fresh shrimp into pasta mixture. Continue as directed.

Makes 6 (1 2/3-cup) servings. Per serving: 849 calories, 46 g protein, 71 g carbohydrate, 42 g total fat (23 g sat. fat), 188 mg cholesterol, 3 g fiber, 10 g total sugar, 36% Vitamin A, 29% Vitamin C, 1107 mg sodium, 59% calcium, 20% iron

Jalapeño Popper Macaroni and Cheese Variation

Prepare as directed, except omit cheddar, Swiss, and Parmesan cheeses. Whisk 8 ounces shredded Monterey Jack cheese with jalapeño peppers, 4 ounces shredded Gouda cheese, and 4 ounces cut-up cream cheese into white sauce. Stir 3 to 4 fresh jalapeño peppers, seeded and thinly sliced or chopped, and 6 slices crumbled, crisp-cooked bacon into pasta mixture. Continue as directed. If desired, top with 2 slices additional crumbled, crisp-cooked bacon before serving. Makes 6 to 8 (1 1/2-cup) servings.

Per serving: 753 calories, 31 g protein, 70 g carbohydrate, 39 g total fat (22 g sat. fat), 115 mg cholesterol, 3 g fiber, 9 g total sugar, 26% Vitamin A, 10% Vitamin C, 925 mg sodium, 43% calcium, 16 g iron

Pumpkin Macaroni and Cheese Variation

Prepare Four-Cheese Macaroni and Cheese as directed, except substitute white cheddar cheese for the sharp cheddar cheese and fontina cheese for the Swiss cheese. Stir one 15-ounce can pumpkin and 1 tablespoon snipped fresh sage into cheese sauce before adding to pasta.

Nutrition analysis per serving: 765 calories, 37 g protein, 77 g carbohydrate, 34 g total fat (21 g sat. fat), 116 mg cholesterol, 5 g fiber, 11 g total sugar, 242% Vitamin A, 8% Vitamin C, 977 mg sodium, 74% calcium, 23% iron

Truffle Macaroni and Cheese Variation

Prepare Four-Cheese Macaroni and Cheese as directed, except drizzle crumb topping with 1 to 2 tablespoons truffle oil before broiling.

Nutrition analysis per serving: 759 calories, 36 g protein, 72 g carbohydrate, 36 g total fat (20 g sat. fat), 111 mg cholesterol, 3 g fiber, 9 g total sugar, 20% Vitamin A, 2% Vitamin C, 858 mg sodium, 77% calcium, 17% iron